Organic Chemical
retroviral vector Audio
[ reh-troh-vy-rul vek-ter ]
Definitions related to retroviral vector:
  • Any one of the recombinant retroviruses (RNA viruses) designed for gene transfer applications to deliver genetic material of interest into cells. These retroviral vectors are replication defective and have decreased immunogenicity. They are able to efficiently infect dividing cells, and the exogenous genetic material is integrated into the genome of the target cell. Thereby, the expression of the exogenous gene is stable instead of transient as in the case of adenoviral vectors.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • RNA from a virus that is used to insert genetic material into cells.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
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