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Neoplastic Process
rhabdomyosarcoma Audio
rhab·do·my·o·sar·co·ma [ rab-doh-mahy-oh-sahr-koh-muh ]
Subclass of:
Myosarcoma
Definitions related to rhabdomyosarcoma:
  • (rhabdomyosarcoma, malignant) A malignant mesenchymal neoplasm arising from skeletal muscle.
    CDISC Terminology
    Clinical Data Interchange Standards Consortium (CDISC), 2021
  • A malignant neoplasm arising from skeletal myocytes.
    NICHD Pediatric Terminology
    U.S. National Cancer Institute, 2021
  • A malignant soft tissue tumor which develops from cells of striated muscle. It is the most common form of tumor found in children and adolescents.
    OrphaNet
    INSERM, 2021
  • A malignant solid tumor arising from mesenchymal tissues which normally differentiate to form striated muscle. It can occur in a wide variety of sites. It is divided into four distinct types: pleomorphic, predominantly in male adults; alveolar (RHABDOMYOSARCOMA, ALVEOLAR), mainly in adolescents and young adults; embryonal (RHABDOMYOSARCOMA, EMBRYONAL), predominantly in infants and children; and botryoidal, also in young children. It is one of the most frequently occurring soft tissue sarcomas and the most common in children under 15. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p2186; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, pp1647-9)
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • A rare aggressive malignant mesenchymal neoplasm arising from skeletal muscle. It usually occurs in children and young adults. Only a small percentage of tumors arise in the skeletal muscle of the extremities. The majority arise in other anatomic sites.
    NCI
    U.S. National Cancer Institute, 2021
  • Cancer that forms in the soft tissues in a type of muscle called striated muscle. Rhabdomyosarcoma can occur anywhere in the body.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • Highly malignant tumor of striated muscle derived from primitive mesenchymal cells and exhibiting differentiation along rhabdomyoblastic lines.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • Rhabdomyosarcoma is a childhood cancer arising from embryonal mesenchymal cells that have potential to differentiate into skeletal muscle cells. It can arise from almost any type of muscle tissue in any location, resulting in highly variable clinical manifestations. Cancers are typically detected by CT or MRI, and diagnosis is confirmed...
    Merck Manuals
    Merck & Co., Inc., 2025
  • Rhabdomyosarcoma (RMS) is a rare type of cancer that forms in soft tissue - specifically skeletal muscle tissue or sometimes hollow organs such as the bladder or uterus. RMS can occur at any age, but it most often affects children.
    Mayo Clinic
    Mayo Foundation for Medical Education and Research, 2025
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.

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