Disease or Syndrome
rheumatoid arthritis
rheu·ma·toid ar·thri·tis [ roo-muh-toyd ar-thry-tis ]
Subclass of:
Autoimmune Diseases;
Rheumatism;
Arthritis
Also called:
RA
Definitions related to rheumatoid arthritis:
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A chronic, inflammatory condition manifesting primarily as a symmetric, erosive, polyarthritis that spares the axial skeleton and is typically associated with rheumatoid factor and anti-citrullinated protein antibodies.NICHD Pediatric TerminologyU.S. National Cancer Institute, 2021
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A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor.NCI ThesaurusU.S. National Cancer Institute, 2021
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An autoimmune disease that causes pain, swelling, and stiffness in the joints, and may cause severe joint damage, loss of function, and disability. The disease may last from months to a lifetime, and symptoms may improve and worsen over time.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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An inflammatory autoimmune disease that typically attacks the connective tissue of the joints, causing them to become painful, inflamed, and sometimes deformed.Harvard Dictionary of Health TermsHarvard Medical Publishing, 2011
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Chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures; etiology is unknown, but autoimmune mechanisms have been implicated.CRISP ThesaurusNational Institutes of Health, 2006
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Inflammatory changes in the synovial membranes and articular structures with widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, as well as atrophy and rarefaction of bony structures.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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Rheumatoid arthritis (RA) is a form of arthritis that causes pain, swelling, stiffness and loss of function in your joints. It can affect any joint but is common in the wrist and fingers. More women than men get rheumatoid arthritis. It often starts in middle age and is most common in older people. You might have the disease for only a short time, or symptoms might come and go. The severe form can last a lifetime. Rheumatoid arthritis is different from osteoarthritis, the common arthritis that often comes with older age. RA can affect body parts besides joints, such as your eyes, mouth and lungs. RA is an autoimmune disease, which means the arthritis results from your immune system attacking your body's own tissues. No one knows what causes rheumatoid arthritis. Genes, environment, and hormones might contribute. Treatments include medicine, lifestyle changes, and surgery. These can slow or stop joint damage and reduce pain and swelling. NIH: National Institute of Arthritis and Musculoskeletal and Skin DiseasesMedlinePlusU.S. National Library of Medicine, 2021
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(arthritis, rheumatoid) A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that primarily involves the joints. RA causes damage mediated by cytokines, chemokines, and metalloproteases. Characteristically, peripheral joints (eg, wrists, metacarpophalangeal joints) are symmetrically inflamed, leading to progressive destruction of articular...Merck & Co., Inc., 2020
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Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease of unknown cause. The hallmark feature of this condition is persistent symmetric polyarthritis (synovitis) that affects the hands and feet, though any joint lined by a synovial membrane may be involved.WebMD, 2019
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Rheumatoid arthritis is a chronic inflammatory disorder that can affect more than just your joints. In some people, the condition can damage a wide variety of body systems, including the skin, eyes, lungs, heart and blood vessels.Mayo Foundation for Medical Education and Research
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Rheumatoid arthritis (RA) is a chronic inflammatory condition affecting around 1% of the population, making it the most common inflammatory arthritis seen by physicians. It primarily affects the small joints of the hands and feet and, if not treated aggressively, can be a major cause of work loss, decreased quality of life, need for...Athenahealth, Inc., 2019
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Rheumatoid arthritis, chronic, frequently progressive disease in which inflammatory changes occur throughout the connective tissues of the body. Inflammation and thickening of the synovial membranes (the sacs holding the fluid that lubricates the joints) cause irreversible damage to the joint...Encyclopedia Britannica, Inc., 2020
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