Antibiotic
rifabutin
[ rih-fuh-byoo-tin ]
Brand Names:
Mycobutin; Talicia
Effect:
Cellular Growth Phase Reduction; Decreased Protein Synthesis; Decreased Transcription to RNA
May Prevent:
Mycobacterium avium-intracellulare Infection; Tuberculosis, Pulmonary
May Treat:
Mycobacterium avium-intracellulare Infection;
Tuberculosis, Pulmonary
More Information:
Definitions related to rifabutin:
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A broad-spectrum antibiotic that is being used as prophylaxis against disseminated Mycobacterium avium complex infection in HIV-positive patients.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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A drug used to prevent the spread of a bacterium called in patients with advanced HIV (the virus that causes AIDS) infection. It blocks an enzyme that the bacteria need to grow. It is a type of antibiotic.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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A semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits bacterial DNA-dependent RNA polymerase, thereby suppressing the initiation of RNA formation and leading to inhibition of RNA synthesis and transcription. (NCI04)NCI ThesaurusU.S. National Cancer Institute, 2021
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Broad-spectrum antibiotic that is being used as prophylaxis against disseminated Mycobacterium avium complex infection in HIV-positive patients.CRISP ThesaurusNational Institutes of Health, 2006
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