Pharmacologic Substance
rifaximin
Brand Names:
XIFAXAN
Effect:
Cellular Growth Phase Reduction; Decreased Protein Synthesis; Decreased RNA Replication; Decreased Transcription to RNA
May Prevent:
Hepatic Encephalopathy
May Treat:
Diarrhea; Irritable Bowel Syndrome
More Information:
ChemID; DrugBank; DailyMed; DrugInfo; PDR
Definitions related to rifaximin:
  • A synthetic rifamycin derivative and anti-bacterial agent that is used for the treatment of GASTROENTERITIS caused by ESCHERICHIA COLI INFECTIONS. It may also be used in the treatment of HEPATIC ENCEPHALOPATHY.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • An orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. Rifaximin binds to the beta-subunit of bacterial DNA-dependent RNA polymerase, inhibiting bacterial RNA synthesis and bacterial cell growth. As rifaximin is not well absorbed, its antibacterial activity is largely localized to the gastrointestinal tract.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.