Disease or Syndrome
scleritis
scle·ri·tis [ skli-rahy-tis ]
Subclass of:
Scleral Diseases
Etymology:
Greek skleros = hard + -itis = inflammation
Descriptive of its relative toughness that the outer layer of the eye is named the sclera.
Descriptive of its relative toughness that the outer layer of the eye is named the sclera.
Definitions related to scleritis:
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Inflammation of the sclera.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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Refers to any inflammation of the sclera including episcleritis, a benign condition affecting only the episclera, which is generally short-lived and easily treated. Classic scleritis, on the other hand, affects deeper tissue and is characterized by higher rates of visual acuity loss and even mortality, particularly in necrotizing form. Its characteristic symptom is severe and general head pain. Scleritis has also been associated with systemic collagen disease. Etiology is unknown but is thought to involve a local immune response. Treatment is difficult and includes administration of anti-inflammatory and immunosuppressive agents such as corticosteroids. Inflammation of the sclera may also be secondary to inflammation of adjacent tissues, such as the conjunctiva.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Scleritis is a severe, destructive, vision-threatening inflammation involving the deep episclera and sclera. Symptoms are moderate to marked pain, hyperemia of the globe, lacrimation, and photophobia. Diagnosis is clinical. Treatment is with systemic corticosteroids and possibly immunosuppressants.Merck & Co., Inc., 2020
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Scleritis is a chronic, painful, and potentially blinding inflammatory disease that is characterized by edema and cellular infiltration of the scleral and episcleral tissues. Scleritis is commonly associated with systemic autoimmune disorders, including rheumatoid arthritis, systemic lupus erythematosus, relapsing polychondritis,...WebMD, 2019
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Scleritis, inflammation of the sclera, the white part of the eye. The inflammation is immune-mediated and is commonly associated with underlying systemic infections, such as shingles (herpes zoster), syphilis, and tuberculosis, or with autoimmune diseases, such as rheumatoid arthritis and systemic...Encyclopedia Britannica, Inc., 2020
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