Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.

The destruction or infection of tissues by disease-causing organisms, usually accompanied by a fever.

Sepsis is your body's overactive and extreme response to an infection. Sepsis is a life-threatening medical emergency. Without quick treatment, it can lead to tissue damage, organ failure, and even death. Sepsis happens when an infection you already have triggers a chain reaction throughout your body. Bacterial infections are the most common cause, but other types of infections can also cause it. The infections are often in the lungs, stomach, kidneys, or bladder. It's possible for sepsis to begin with a small cut that gets infected or with an infection that develops after surgery. Sometimes, sepsis can occur in people who didn't even know that they had an infection. Anyone with an infection could get sepsis. But certain people are more likely to develop it: Adults 65 or older; People with chronic (long-lasting) conditions, such as diabetes, lung disease, cancer, and kidney disease; People with weakened immune systems; Pregnant women; Children younger than one. Sepsis can cause one or more of these symptoms: Rapid breathing and heart rate; Shortness of breath; Confusion or disorientation; Extreme pain or discomfort; Fever, shivering, or feeling very cold; Clammy or sweaty skin. It's important to get medical care right away if you think you might have sepsis or if your infection is not getting better or is getting worse. Severe cases of sepsis can lead to septic shock, where your blood pressure drops to a dangerous level and multiple organs can fail. To find out if you have sepsis, your health care provider: Will take your medical history, which includes asking about your symptoms; Will do a physical exam, which includes checking vital signs (your temperature, blood pressure, heart rate, and breathing); Will likely order lab tests that check for signs of infection or organ damage; May order imaging tests such as an x-ray or a CT scan to find the location of the infection. Many of the signs and symptoms of sepsis can also be caused by other medical conditions. This may make sepsis hard to diagnose in its early stages. It is very important to get treatment right away. Treatment usually includes: Antibiotics.; Maintaining blood flow to organs. This may involve getting oxygen and intravenous (IV) fluids.; Treating the source of the infection.; If needed, medicines to increase blood pressure. In serious cases, you might need kidney dialysis or a breathing tube. Some people need surgery to remove tissue damaged by the infection. To prevent sepsis, you should try to prevent getting an infection: Take good care of any chronic health conditions that you have; Get recommended vaccines; Practice good hygiene, such as handwashing; Keep cuts clean and covered until healed. NIH: National Institute of General Medical SciencesCenters for Disease Control and Prevention

A disorder characterized by the presence of pathogenic microorganisms in the blood stream that cause a rapidly progressing systemic reaction that may lead to shock.

Sepsis is a potentially life-threatening condition caused by the body's response to an infection. The body normally releases chemicals into the bloodstream to fight an infection. Sepsis occurs when the body's response to these chemicals is out of balance, triggering changes that can damage multiple organ systems.

Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to an infection. The definition of sepsis was updated in 2016 following publication of the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).

Sepsis, systemic inflammatory condition that occurs as a complication of infection and in severe cases may be associated with acute and life-threatening organ dysfunction. Worldwide, sepsis has long been a common cause of illness and mortality in hospitals, intensive care units, and emergency...