Disease or Syndrome
sinus histiocytosis
Subclass of:
Histiocytosis, Non-Langerhans-Cell
Definitions related to sinus histiocytosis:
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A morphologic finding indicating the presence of histiocytic infiltrates within distended lymph node sinuses.NCI ThesaurusU.S. National Cancer Institute, 2021
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(histiocytosis, sinus) Benign, non-Langerhans-cell, histiocytic proliferative disorder that primarily affects the lymph nodes. It is often referred to as sinus histiocytosis with massive lymphadenopathy.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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(sinus histiocytosis with massive lymphadenopathy) A rare disorder of unknown etiology characterized by distention of the lymph node sinuses and sinusoidal histiocytic infiltration. The histiocytes characteristically contain ingested lymphocytes. Patients present with cervical lymphadenopathy, fever, leukocytosis, and hypergammaglobulinemia. It can affect extranodal sites, including skin, bones, and the respiratory tract. It usually regresses spontaneously.NCI ThesaurusU.S. National Cancer Institute, 2021
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Rosai-Dorfman disease is a rare disorder characterized by accumulation of histiocytes and massive lymphadenopathy, particularly in the neck and head. Rosai-Dorfman disease is most common among patients 20 years, particularly blacks. The cause is unknown.Merck & Co., Inc., 2020
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Rosai-Dorfman disease was first described by Rosai and Dorfman in 1969. It is a benign disease which is characterized by over-production and accumulation of a specific type of white blood cell (histiocyte) in the lymph nodes of the body, most often those of the neck (cervical). Other lymph node groups may also be involved and, in some...National Center for Advancing Translational Sciences
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