Pharmacologic Substance
sodium citrate
so·di·um cit·rate
Brand Names:
BSS Ophthalmic Solution; Citra pH; Cytra 2; Cytra-3; Oracit; Regiocit
Effect:
Increased Intravascular Volume; Increased Renal HCO3- Excretion; Unknown Physiological Effect
May Treat:
Urinary Calculi
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to sodium citrate:
  • A drug used in the treatment of metabolic acidosis (a disorder in which the blood is too acidic).
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • Sodium salts of citric acid that are used as buffers and food preservatives. They are used medically as anticoagulants in stored blood, and for urine alkalization in the prevention of KIDNEY STONES.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • The sodium salt of citrate with alkalinizing activity. Upon absorption, sodium citrate dissociates into sodium cations and citrate anions; organic citrate ions are metabolized to bicarbonate ions, resulting in an increase in the plasma bicarbonate concentration, the buffering of excess hydrogen ion, the raising of blood pH, and potentially the reversal of acidosis. In addition, increases in free sodium load due to sodium citrate administration may increase intravascular blood volume, facilitating the excretion of bicarbonate compounds and an anti-urolithic effect.
    NCI
    U.S. National Cancer Institute, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.