Pharmacologic Substance
sucralfate Audio
su·cral·fate [ soo-kruh l-feyt ]
Brand Names:
Carafate
Effect:
Gastric Acid Alteration
May Prevent:
Duodenal Ulcer
May Treat:
Duodenal Ulcer; Esophagitis; Gastritis; Pneumonia; Stomach Ulcer; Stomatitis
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to sucralfate:
  • A basic aluminum complex of sulfated sucrose.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • A drug used to treat ulcers. It adheres to proteins at the ulcer site and forms a protective coating over the ulcer. Sucralfate is also used to treat mucositis.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • A nonabsorbable, aluminum salt of sucrose orasulfate with anti-ulcer, mucosa-protective and potentially anti-mucositis activity. Negatively charged sucralfate binds, through ionic bond formation, to positively charged proteins on mucosal surfaces, thereby creating a protective coating and physical barrier. This agent may also enhance the production of prostaglandin E2 locally, thereby promoting mucus production, increasing mucosal blood flow and stimulating epithelial proliferation and may contribute to the healing of damaged mucosa.
    NCI
    U.S. National Cancer Institute, 2021
Try this search on: Farlex, Merriam-Webster, Oxford Dictionary, or Wordnik

This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.