Antibiotic
sulfanilamide
sul·fa·nil·a·mide [ suhl-fuh-nil-uh-mahyd, -mid ]
Brand Names:
AVC brand of sulfanilamide
Effect:
Decreased Folic Acid Modification
May Treat:
Candidiasis, Vulvovaginal
Definitions related to sulfanilamide:
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A short-acting sulfonamide used as an anti-infective agent. It has lower anti-bacterial activity than SULFAMETHOXAZOLE.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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An organic sulfur compound structurally similar to p-aminobenzoic acid (PABA) with antibacterial property. Sulfanilamide competes with PABA for the bacterial enzyme dihydropteroate synthase, thereby preventing the incorporation of PABA into dihydrofolic acid, the immediate precursor of folic acid. This leads to an inhibition of bacterial folic acid synthesis and de novo synthesis of purines and pyrimidines, ultimately resulting in cell growth arrest and cell death.NCI ThesaurusU.S. National Cancer Institute, 2021
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Potent antibacterial agent, the first of the sulfonamides discovered.CRISP ThesaurusNational Institutes of Health, 2006
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