Pharmacologic Substance
sulfonamide
sul·fon·a·mide [ suhl-fon-uh-mahyd, -mid, suhl-fuh-nam-ahyd, -id ]
Subclass of:
Sulfones;
Amides
Definitions related to sulfonamides:
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The chemical group -SO2NH2; do not confuse with BENZENESULFONAMIDE, which are the family of bacteriocidal "sulfa drugs" and diuretics related to sulfanilamide.CRISP ThesaurusNational Institutes of Health, 2006
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A group of compounds that contain the structure SO2NH2.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Sulfonamides are synthetic bacteriostatic antibiotics that competitively inhibit conversion of p-aminobenzoic acid to dihydropteroate, which bacteria need for folate synthesis and ultimately purine and DNA synthesis. Humans do not synthesize folate but acquire it in their diet, so their DNA synthesis is less affected.Merck & Co., Inc., 2020
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