Pharmacologic Substance
terbinafine
Brand Names:
Lamisil; Silka Cream
Effect:
Decreased Cell Wall Integrity
May Treat:
Candidiasis, Chronic Mucocutaneous;
Onychomycosis;
Tinea Capitis;
Tinea Pedis;
Tinea Versicolor
More Information:
Definitions related to terbinafine:
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A naphthalene derivative that inhibits fungal SQUALENE EPOXIDASE and is used to treat DERMATOMYCOSES of the skin and nails.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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A synthetic allylamine derivative with antifungal activity. Terbinafine exerts its effect through inhibition of squalene epoxidase, thereby blocking the biosynthesis of ergosterol, an important component of fungal cell membranes. As a result, this agent disrupts fungal cell membrane synthesis and inhibits fungal growth.NCI ThesaurusU.S. National Cancer Institute, 2021
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