Disease or Syndrome
thalassemia

thal·as·se·mi·a [ thal-uh-see-mee-uh ]
Subclass of:
Anemia, Hemolytic, Congenital;
Hemoglobinopathies
Etymology:
Greek thalassa = the sea + haima = blood
This erythroblastic anemia is so called because it occurs in children of parents from countries bordering the Mediterranean sea.
This erythroblastic anemia is so called because it occurs in children of parents from countries bordering the Mediterranean sea.
Also called:
Cooley's anemia; Mediterranean anemia; Thalassemia Major and Minor
Definitions related to thalassemia:
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A group of hereditary hemolytic anemias in which there is decreased synthesis of one or more hemoglobin polypeptide chains. There are several genetic types with clinical pictures ranging from barely detectable hematologic abnormality to severe and fatal anemia.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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An inherited blood disorder characterized by a decreased synthesis of one of the polypeptide chains that form hemoglobin. Anemia results from this abnormal hemoglobin formation.NCI ThesaurusU.S. National Cancer Institute, 2021
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Heterogeneous group of hereditary hemolytic anemias which have in common a decreased rate of synthesis of one or more hemoglobin polypeptide chains.CRISP ThesaurusNational Institutes of Health, 2006
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Thalassemias are inherited blood disorders. If you have one, your body makes fewer healthy red blood cells and less hemoglobin. Hemoglobin is a protein that carries oxygen to the body. That leads to anemia. Thalassemias occur most often among people of Italian, Greek, Middle Eastern, Southern Asian, and African descent. Thalassemias can be mild or severe. Some people have no symptoms or mild anemia. The most common severe type in the United States is called Cooley's anemia. It usually appears during the first two years of life. People with it may have severe anemia, slowed growth and delayed puberty, and problems with the spleen, liver, heart, or bones. Doctors diagnose thalassemias using blood tests. Treatments include blood transfusions and treatment to remove excess iron from the body. If you have mild symptoms or no symptoms, you may not need treatment. In some severe cases, you may need a bone marrow transplant. NIH: National Heart, Lung, and Blood InstituteMedlinePlusU.S. National Library of Medicine, 2021
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Thalassemias are a group of inherited microcytic, hemolytic anemias characterized by defective hemoglobin synthesis. Alpha-thalassemia is particularly common among people of African, Mediterranean, or Southeast Asian ancestry. Beta-thalassemia is more common among people of Mediterranean, Middle Eastern, Southeast Asian, or Indian...Merck & Co., Inc., 2020
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Thalassemias are a group of inherited microcytic, hemolytic anemias characterized by defective hemoglobin synthesis. Alpha-thalassemia is particularly common among people of African, Mediterranean, or Southeast Asian ancestry. Beta-thalassemia is more common among people of Mediterranean, Middle Eastern, Southeast Asian, or Indian...Merck & Co., Inc., 2020
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Thalassemia (thal-uh-SEE-me-uh) is an inherited blood disorder that causes your body to have less hemoglobin than normal. Hemoglobin enables red blood cells to carry oxygen. Thalassemia can cause anemia, leaving you fatigued.Mayo Foundation for Medical Education and Research
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Thalassemia is an inherited blood disorder that reduces the production of functional hemoglobin (the protein in red blood cells that carries oxygen). This causes a shortage of red blood cells and low levels of oxygen in the bloodstream, leading to a variety of health problems. There are two main types of thalassemia, alpha thalassemia...National Center for Advancing Translational Sciences
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Thalassemia, group of blood disorders characterized by a deficiency of hemoglobin, the blood protein that transports oxygen to the tissues. Thalassemia (Greek: "sea blood") is so called because it was first discovered among peoples around the Mediterranean Sea, among whom its incidence is high....Encyclopedia Britannica, Inc., 2020
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