A glycoprotein that is incorporated into cells, including blood platelets (thrombocytes) from which they are named. Five distinct forms have been identified, and they play roles in a variety of processes such as: blood coagulation, cell adhesion, platelet aggregation, cell proliferation, angiogenesis, tumor metastasis, and tissue repair.

Multifunctional glycoprotein secreted by endothelial cells and by alpha granules of platelets following activation by thrombin; interacts with a wide variety of molecules to play a role in platelet aggregation, tumor metastasis, vascular smooth muscle growth, and microorganism adhesion.

A family of related, adhesive glycoproteins which are synthesized, secreted, and incorporated into the extracellular matrix of a variety of cells, including alpha granules of platelets following thrombin activation and endothelial cells. They interact with a number of BLOOD COAGULATION FACTORS and anticoagulant factors. Five distinct forms have been identified, thrombospondin 1, -2, -3, -4, and cartilage oligomeric matrix protein (COMP). They are involved in cell adhesion, platelet aggregation, cell proliferation, angiogenesis, tumor metastasis, VASCULAR SMOOTH MUSCLE growth, and tissue repair.