Pharmacologic Substance
ticlopidine
Brand Names:
Ticlid
Effect:
Decreased Platelet Aggregation
May Prevent:
Ischemia; Stroke; Thromboembolism; Venous Thrombosis
May Treat:
Intracranial Embolism and Thrombosis
More Information:
Definitions related to ticlopidine:
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A thienopyridine derivative with anticoagulant activity. Ticlopidine inhibits adenosine-diphosphate (ADP) binding to its platelet receptor. This prevents ADP activation and inhibits platelet expression of the glycoprotein (GP) IIb/IIIA receptors, binding of fibrinogen to platelet glycoprotein GP IIb-IIIa and platelet-platelet interaction. This results in increased bleeding time.NCI ThesaurusU.S. National Cancer Institute, 2021
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An antiplatelet drug that prevents the formation of blood clots.Harvard Dictionary of Health TermsHarvard Medical Publishing, 2011
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An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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