Pharmacologic Substance
torsemide
Brand Names:
Demadex
Effect:
Decreased Blood Pressure; Decreased Intravascular Volume; Increased Loop of Henle Ca++ Excretion; Increased Loop of Henle Cl- Excretion; Increased Loop of Henle K+ Excretion; Increased Loop of Henle Mg++ Excretion; Increased Loop of Henle Na+ Excretion
May Treat:
Acute Kidney Injury; Ascites; Edema; Heart Failure; Hypertension; Kidney Failure, Chronic; Liver Cirrhosis; Nephrotic Syndrome; Pulmonary Edema
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to torsemide:
  • A pyridine and sulfonamide derivative that acts as a sodium-potassium chloride symporter inhibitor (loop diuretic). It is used for the treatment of EDEMA associated with CONGESTIVE HEART FAILURE; CHRONIC RENAL INSUFFICIENCY; and LIVER DISEASES. It is also used for the management of HYPERTENSION.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • An anilinopyridine sulfonylurea belonging to the class of loop diuretics. Torsemide has a prolonged duration of action compared to other loop diuretics, is extensively protein bound in plasma and has a relatively long half-life.
    NCI
    U.S. National Cancer Institute, 2021
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