Receptor
transferrin receptor
trans·fer·rin re·cep·tor [ trans-fer-in ri-sep-ter ]
Subclass of:
Transferrin-Binding Proteins;
Receptors, Cell Surface
Definitions related to transferrin receptor:
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Major vehicle for cellular uptake of iron; receptor expression is tightly regulated by available iron, via an "iron-responsive element" (IRE) on its mRNA which prevents translation when occupied by an iron- sensitive binding protein.CRISP ThesaurusNational Institutes of Health, 2006
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(receptors, transferrin) Membrane glycoproteins found in high concentrations on iron-utilizing cells. They specifically bind iron-bearing transferrin, are endocytosed with its ligand and then returned to the cell surface where transferrin without its iron is released.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Transferrin receptors, which are blood proteins, may be elevated in persons with iron deficiency. Transferrin receptor testing is used to measure the level of soluble transferrin receptors, thereby aiding in the evaluation of iron deficiency and in the diagnosis of iron-deficiency anemia.WebMD, 2019
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