Receptor
notch receptors
notch re·cep·tors
Subclass of:
Receptors, Cell Surface; TRANSCRIPTION FACTOR
Definitions related to receptors, notch:
  • (notch family) A family of transmembrane receptors with multiple extracellular EGF repeats and a DSL (notch) domain. These proteins interact with their cell-bound ligands (from the delta and serrate protein families). This interaction stimulates cell-cell signaling pathways that regulate cell fate decisions during embryogenesis.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • A family of conserved cell surface receptors that contain EPIDERMAL GROWTH FACTOR repeats in their extracellular domain and ANKYRIN REPEATS in their cytoplasmic domains. The cytoplasmic domains are released upon ligand binding and translocate to the cell nucleus, where they act as transcription factors.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
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