Gene or Genome
trd gene
Subclass of:
Genes, T-Cell Receptor
Definitions related to trd gene:
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(t-cell receptor delta locus) This region represents the germline organization of the T cell receptordelta locus. The delta locus includes V (variable), J (joining), diversity (D), and C (constant) segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several D and J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. (from LocusLink)NCI ThesaurusU.S. National Cancer Institute, 2021
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(genes, t-cell receptor delta) DNA sequences encoding the delta chain of the T-cell receptor. The delta-chain locus is located entirely within the alpha-chain locus.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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