Pharmacologic Substance
tributyrin Audio
[ try-byoo-tuh-rin ]
Definitions related to tributyrin:
  • A triglyceride drug that may inhibit cell growth and induce cell differentiation. Differentiating agents may be effective in changing cancer cells back into normal cells.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • A triglyceride prodrug of butyric acid with potential antineoplastic activity. Butyrate, the active metabolite of tributyrin, inhibits histone deacetylase, resulting in increased differentiation, decreased proliferation, cell cycle arrest, and apoptosis in some tumor cell lines. (NCI04)
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
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