Disease or Syndrome
tuberculosis
tu·ber·cu·lo·sis [ too-bur-kyuh-loh-sis, tyoo- ]
Subclass of:
Mycobacterium Infections
Etymology:
Latin tuber = a knot or collection + -osis = condition
Also called:
TB
Definitions related to tuberculosis:
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A chronic, recurrent infection caused by the bacterium Mycobacterium tuberculosis. Tuberculosis (TB) may affect almost any tissue or organ of the body with the lungs being the most common site of infection. The clinical stages of TB are primary or initial infection, latent or dormant infection, and recrudescent or adult-type TB. Ninety to 95% of primary TB infections may go unrecognized. Histopathologically, tissue lesions consist of granulomas which usually undergo central caseation necrosis. Local symptoms of TB vary according to the part affected; acute symptoms include hectic fever, sweats, and emaciation; serious complications include granulomatous erosion of pulmonary bronchi associated with hemoptysis. If untreated, progressive TB may be associated with a high degree of mortality. This infection is frequently observed in immunocompromised individuals with AIDS or a history of illicit IV drug use.NCIU.S. National Cancer Institute, 2021
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A disease caused by Mycobacterium tuberculosis infection that is characterized by the growth of nodules in body tissues, most commonly the lungs, and may be transmitted through droplets from the throat or lungs of individuals with the active respiratory disease.NICHD Pediatric TerminologyU.S. National Cancer Institute, 2021
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Any of the infectious diseases of man and other animals caused by species of MYCOBACTERIUM TUBERCULOSIS.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2025
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Infectious diseases of man and animals caused by Mycobacterium species and characterized by formation of tubercles and caseous necrosis in the tissues; any organ may be affected but in man the lung is the major seat of the disease and the usual portal through which the infection reaches other organs.CRISP ThesaurusNational Institutes of Health, 2006
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Tuberculosis (TB) is a bacterial disease that usually attacks the lungs. But it can also attack other parts of the body, including the kidneys, spine, and brain. Not everyone infected with TB bacteria (germs) becomes sick. So, there are two types of TB conditions: Inactive (latent) TB infection, where the TB germs live in your body but don't make you sick.; TB disease (active TB) where you get sick from the TB germs. TB disease can almost always be cured with antibiotics. But if it's not treated properly, it can be fatal. TB is found in the U.S., but it is more common in certain other countries. TB is caused by bacteria (germs) called Mycobacterium tuberculosis. The germs spread from person to person through the air. People who have TB disease in their throat or lungs spread the germs in the air when they cough, sneeze, talk, or sing. If you breathe in the air that has the germs, you can get TB. TB is not spread by touching, kissing, or sharing food or dishes. You're more likely to catch TB from people you live or work with than from people you see for shorter amounts of time. Anyone who is near a person with TB disease can get infected with the germs. You are more likely to be near someone with TB disease if you: Were born in or often travel to countries where TB disease is common; Are a health care worker; Work or live in a place where TB is more common, such as shelters for people without homes, jails, and nursing homes. Certain people are more likely to get sick with TB disease after they get infected. They include people who: Have HIV; Became infected with TB in the last 2 years; Have other diseases, such as diabetes, that make it hard for your body to fight TB germs; Have alcohol use disorder (AUD) or inject illegal drugs; Were not treated correctly for TB in the past; Are under age 5; Are an older adult; Take medicines that weaken the immune system, such as medicines taken after an organ transplant, steroids, and specialized treatments for certain autoimmune diseases. Most people who have TB germs in their bodies don't get sick with TB disease. Instead, they have inactive TB infection. With an inactive TB infection, you: Don't have symptoms; Can't spread TB to others; Could get sick with active TB disease in the future if your immune system becomes weak for another reason; Need to take medicine to prevent getting sick with active TB disease in the future. If you have TB disease, the TB germs are active, meaning that they are growing (multiplying) inside your body and making you sick. If the TB is growing in your lungs or throat, you can spread the TB germs to other people. You can get sick with TB disease weeks to years after you're infected with TB germs. With TB disease, your symptoms will depend on where the TB is growing in your body: General symptoms may include: Chills and fever; Night sweats (heavy sweating during sleep); Losing weight without trying; Loss of appetite; Weakness or fatigue.; Symptoms from TB disease in your lungs may include: A cough that lasts longer than 3 weeks; Coughing up blood or sputum (a thick mucus from the lungs); Chest pain. . Your health care provider or your local health department can test you to find out if you have TB germs in your body. They will give you either a TB skin or blood test. If your test shows that you have TB germs, you'll need to have other tests to see if...MedlinePlusU.S. National Library of Medicine, 2025
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Tuberculosis (TB) is a chronic, progressive mycobacterial infection, often with a period of latency following initial infection. TB most commonly affects the lungs. Symptoms include productive cough, fever, weight loss, and malaise. Diagnosis is most often by sputum smear and culture and, increasingly, by rapid molecular-based diagnostic...Merck & Co., Inc., 2025
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Tuberculosis (TB) (see the image below), a multisystemic disease with myriad presentations and manifestations, is the most common cause of infectious disease�related mortality worldwide. Although TB rates are decreasing in the United States, the disease is becoming more common in many parts of the world.WebMD, 2025
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Tuberculosis (TB) is a potentially serious infectious disease that mainly affects your lungs. The bacteria that cause tuberculosis are spread from one person to another through tiny droplets released into the air via coughs and sneezes.Mayo Foundation for Medical Education and Research, 2025
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Tuberculosis (TB), infectious disease that is caused by the tubercle bacillus, Mycobacterium tuberculosis. In most forms of the disease, the bacillus spreads slowly and widely in the lungs, causing the formation of hard nodules (tubercles) or large cheeselike masses that break down the respiratory...Encyclopedia Britannica, Inc., 2025
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