Neoplastic Process
uveal melanoma
[ yoo-vee-al mel-uh-noh-muh ]
Definitions related to uveal melanoma:
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(melanoma, uveal, malignant) A malignant neoplasm of the uvea composed of melanocytes.CDISC TerminologyClinical Data Interchange Standards Consortium (CDISC), 2021
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A malignant melanoma originating within the eye. The tumor originates from the melanocytes in the uvea (which comprises the iris, ciliary body, and choroid).Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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A melanoma derived from melanocytes of the uveal tract. It is the most common primary intraocular tumor in the United States and Western Europe. Similar to melanoma of the skin, it is rare in Africa and Asia. Diagnostic procedures include ophthalmoscopic exam, fluorescein angiography and ultrasound. Treatment includes: surgical excision of the eye, iridocyclectomy and tumor resection. Recent treatments also include radiotherapy or photo coagulation. Classification of uveal melanomas recognizes four cell types within these tumors: epithelioid, intermediate, mixed cell, and spindle cell types. The spindle cell type uveal melanomas are further sub-classified as spindle cell type A and spindle cell type B.NCI ThesaurusU.S. National Cancer Institute, 2021
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(intraocular melanoma) A rare cancer of melanocytes (cells that produce the pigment melanin) found in the eye.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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Intraocular melanoma is a cancer of the pigment-producing cells (melanocytes) in the middle layer of the eye, called the uveal tract. The uveal tract has 3 main parts: (1) the choroid (the tissue layer filled with blood vessels); (2) the ciliary body (the ring of muscle tissue that changes the size of the pupil and the shape of the...National Center for Advancing Translational Sciences
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