Pharmacologic Substance
vadimezan
Definitions related to vadimezan:
  • A fused tricyclic analogue of flavone acetic acid with potential antineoplastic activity. Vadimezan induces the cytokines tumor necrosis alpha (TNF-alpha), serotonin and nitric oxide, resulting in hemorrhagic necrosis and a decrease in angiogenesis. This agent also stimulates the anti-tumor activity of tumor-associated macrophages.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • (dimethylxanthenone acetic acid) An anticancer drug that is a type of angiogenesis inhibitor.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
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