Pharmacologic Substance
valganciclovir Audio
[ val-gan-sy-kloh-veer ]
Brand Names:
Valcyte
Effect:
Decreased DNA Integrity; Decreased DNA Replication
May Prevent:
Cytomegalovirus Infections
May Treat:
AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to valganciclovir:
  • A ganciclovir prodrug and antiviral agent that is used to treat CYTOMEGALOVIRUS RETINITIS in patients with AIDS, and for the prevention of CYTOMEGALOVIRUS INFECTIONS in organ transplant recipients who have received an organ from a CMV-positive donor.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • A synthetic prodrug of ganciclovir, a nucleoside analogue of 2'-deoxyguanosine, with antiviral activity. After phosphorylation, valganciclovir is incorporated into DNA, resulting in inhibition of viral DNA polymerase, viral DNA synthesis, and viral replication. (NCI04)
    NCI
    U.S. National Cancer Institute, 2021
  • An antiviral agent that is being studied as a treatment for AIDS-related cytomegalovirus. It is changed in the body to ganciclovir.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
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