Pharmacologic Substance
vidarabine phosphate
Subclass of:
Adenine Nucleotides; Arabinonucleotides
Definitions related to vidarabine phosphate:
  • A phosphate salt form of vidarabine, a nucleoside analog with activity against herpes simplex virus and varicella zoster virus. Vidarabine is converted to a monophosphate by viral thymidine kinase and is further modified to a triphosphate form by host enzymes. Vidarabine triphosphate directly inhibits DNA polymerase and also acts as a chain terminator in DNA replication.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • An adenosine monophosphate analog in which ribose is replaced by an arabinose moiety. It is the monophosphate ester of VIDARABINE with antiviral and possibly antineoplastic properties.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
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