Pharmacologic Substance
vinblastine sulfate
vin·blas·tine sul·fate [ vin-blas-teen sul-fayt ]
Effect:
Cellular Growth Phase Arrest; Decreased Mitosis; Increased Cellular Death
May Treat:
Breast Neoplasms;
Choriocarcinoma;
Head and Neck Neoplasms;
Histiocytosis;
Hodgkin Disease;
Kidney Neoplasms;
Lung Neoplasms;
Mycosis Fungoides;
Purpura, Thrombocytopenic, Idiopathic;
Sarcoma, Kaposi;
Testicular Neoplasms
More Information:
Definitions related to vinblastine sulfate:
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A drug used with other drugs to treat several types of cancer, including advanced Hodgkin lymphoma and advanced testicular germinal-cell cancers. It is also being studied in the treatment of other types of cancer. Velban comes from the periwinkle plant Vinca rosea Linn. It blocks cell growth by stopping cell division and may kill cancer cells. It is a type of vinca alkaloid and a type of antimitotic agent.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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The sulfate salt of vinblastine, a natural alkaloid isolated from the plant Catharanthus roseus (Madagascar periwinkle) with antineoplastic properties. Vinblastine disrupts microtubule formation and function during mitosis and interferes with glutamic acid metabolism. (NCI04)NCI ThesaurusU.S. National Cancer Institute, 2021
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