Pharmacologic Substance
vinca alkaloid Audio
[ ving-kuh al-kuh-loid ]
Subclass of:
Secologanin Tryptamine Alkaloids
Definitions related to vinca alkaloids:
  • A type of drug that blocks cell growth by stopping mitosis (cell division). Vinca alkaloids interfere with microtubules (cellular structures that help move chromosomes during mitosis). They are used to treat cancer. A vinca alkaloid is a type of mitotic inhibitor and a type of antimicrotubule agent.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • Nitrogenous basic compounds produced by the Madagascar periwinkle; they are cytotoxic and cell cycle specific for the M phase of cell division.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • A group of indole-indoline dimers which are ALKALOIDS obtained from the VINCA genus of plants. They inhibit polymerization of TUBULIN into MICROTUBULES thus blocking spindle formation and arresting cells in METAPHASE. They are some of the most useful ANTINEOPLASTIC AGENTS.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
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