Pharmacologic Substance
cabergoline
Effect:
Decreased Prolactin Secretion; Increased Dopamine Activity
May Treat:
Adenoma; Hyperprolactinemia; Parkinson Disease
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to cabergoline:
  • A synthetic ergoline derivative and a long-acting dopamine receptor agonist with high affinity for the dopamine D2 receptor. Cabergoline exerts an inhibitory effect on prolactin secretion by acting on dopamine receptors present in pituitary lactotrophs. This drug also binds to dopamine D2 receptors in the corpus striatum, thereby mimicking the actions of dopamine on motor control. Cabergoline also possesses antioxidant and neuroprotective properties due to its free radical scavenging activity. Cabergoline is used in the treatment of Parkinson's disease and in the treatment of hyperprolactinemia.
    NCI
    U.S. National Cancer Institute, 2021
  • An ergoline derivative and dopamine D2-agonist that inhibits PROLACTIN secretion. It is used in the management of HYPERPROLACTINEMIA, and to suppress lactation following childbirth for medical reasons. Cabergoline is also used in the management of PARKINSON DISEASE.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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