Disease or Syndrome
carpal tunnel syndrome
car·pal tun·nel syn·drome
Subclass of:
Cumulative Trauma Disorders;
Nerve compression syndrome;
Median Neuropathy
Also called:
Median nerve entrapment
Definitions related to carpal tunnel syndrome:
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A condition that occurs when the median nerve, which runs from the forearm through the hand, is compressed; symptoms include pain, tingling, and numbness, as well as hand weakness.Harvard Dictionary of Health TermsHarvard Medical Publishing, 2011
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Carpal tunnel syndrome is the name for a group of problems that includes numbness, tingling, weakness, or pain in your wrist or hand. It's a very common condition that happens when a nerve in your wrist becomes squeezed. The carpal tunnel is a narrow opening between the bones in your wrist and the ligament that holds them together. A nerve, called the median nerve, runs from your lower arm through the carpal tunnel and into your hand. This nerve provides feeling to your thumb and first three fingers. It also helps you move your thumb. Tendons also run from your lower arm, through the carpal tunnel, and into your hand. The tendons connect your finger bones to muscles in your arm, so you can bend your fingers. If the tendons become swollen or irritated inside the carpal tunnel, they may press on the nerve. The squeezed nerve may not work well, which can lead to numbness, weakness, and other symptoms of carpal tunnel syndrome. In certain cases, the cause of carpal tunnel syndrome is unknown. But it usually happens from a combination of things that affect the structures in your wrist, such as: Injury to your wrist that causes swelling, such as a sprain or broken bone; Health conditions that can affect your nerves, joints, or other parts of your wrist, for example: Diabetes.; Rheumatoid arthritis.; A cyst or tumor in your wrist.; Changes in certain hormones, which may cause swelling from extra fluid in your body. Examples include an underactive thyroid gland (hypothyroidism), pregnancy and menopause.; Problems with the way your wrist is formed.; Doing the same wrist and hand movements over and over, such as: Assembly line work.; Carpentry or using tools that vibrate.; Knitting, gardening, or sports, such as golf. . Researchers aren't sure whether long-term typing or computer use leads to carpal tunnel syndrome. Carpal tunnel syndrome usually happens only in adults. You're more likely to develop it if you: Are a woman. Women are three times more likely to have carpal tunnel syndrome than men.; Have a health condition that may affect structures in your wrist.; Do activities with repeated hand motions.; Have had a wrist injury.; Have a close relative who has had carpal tunnel syndrome, such as a parent, brother or sister. You may feel numbness, tingling or burning in your fingers, especially in your thumb, index, and middle fingers. Symptoms often affect both hands. In the early stages, symptoms usually: Start slowly in your dominant hand (the one you write with); Happen at night if you sleep with your wrists bent. As symptoms get worse, you may notice: Tingling, pain, or weakness with certain activities, such as driving or holding a phone; Difficulty grasping or holding small things; Feeling like your fingers are swollen when they're not. Without treatment, you could lose feeling in some fingers and have permanent weakness in your thumb. But early diagnosis and treatment can help prevent lasting damage. To find out if you have carpal tunnel syndrome, your health care provider will: Ask about your medical history; Ask about your family health history; Do a physical exam; Order tests if needed, such as:...MedlinePlus GeneticsU.S. National Library of Medicine, 2021
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Entrapment of the MEDIAN NERVE in the carpal tunnel, which is formed by the flexor retinaculum and the CARPAL BONES. This syndrome may be associated with repetitive occupational trauma (CUMULATIVE TRAUMA DISORDERS); wrist injuries; AMYLOID NEUROPATHIES; rheumatoid arthritis (see ARTHRITIS, RHEUMATOID); ACROMEGALY; PREGNANCY; and other conditions. Symptoms include burning pain and paresthesias involving the ventral surface of the hand and fingers which may radiate proximally. Impairment of sensation in the distribution of the median nerve and thenar muscle atrophy may occur. (Joynt, Clinical Neurology, 1995, Ch51, p45)NLM Medical Subject HeadingsU.S. National Library of Medicine, 2025
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Entrapment of the median nerve in the wrist that is characterized by numbness, tingling and painful movement.NCIU.S. National Cancer Institute, 2021
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Carpal tunnel syndrome is the name for a group of problems that includes numbness, tingling, weakness, or pain in your wrist or hand. It's a very common condition that happens when a nerve in your wrist becomes squeezed. The carpal tunnel is a narrow opening between the bones in your wrist and the ligament that holds them together. A nerve, called the median nerve, runs from your lower arm through the carpal tunnel and into your hand. This nerve provides feeling to your thumb and first three fingers. It also helps you move your thumb. Tendons also run from your lower arm, through the carpal tunnel, and into your hand. The tendons connect your finger bones to muscles in your arm, so you can bend your fingers. If the tendons become swollen or irritated inside the carpal tunnel, they may press on the nerve. The squeezed nerve may not work well, which can lead to numbness, weakness, and other symptoms of carpal tunnel syndrome. In certain cases, the cause of carpal tunnel syndrome is unknown. But it usually happens from a combination of things that affect the structures in your wrist, such as: Injury to your wrist that causes swelling, such as a sprain or broken bone; Health conditions that can affect your nerves, joints, or other parts of your wrist, for example: Diabetes.; Rheumatoid arthritis.; A cyst or tumor in your wrist.; Changes in certain hormones, which may cause swelling from extra fluid in your body. Examples include an underactive thyroid gland (hypothyroidism), pregnancy and menopause.; Problems with the way your wrist is formed.; Doing the same wrist and hand movements over and over, such as: Assembly line work.; Carpentry or using tools that vibrate.; Knitting, gardening, or sports, such as golf. . Researchers aren't sure whether long-term typing or computer use leads to carpal tunnel syndrome. Carpal tunnel syndrome usually happens only in adults. You're more likely to develop it if you: Are a woman. Women are three times more likely to have carpal tunnel syndrome than men.; Have a health condition that may affect structures in your wrist.; Do activities with repeated hand motions.; Have had a wrist injury.; Have a close relative who has had carpal tunnel syndrome, such as a parent, brother or sister. You may feel numbness, tingling or burning in your fingers, especially in your thumb, index, and middle fingers. Symptoms often affect both hands. In the early stages, symptoms usually: Start slowly in your dominant hand (the one you write with); Happen at night if you sleep with your wrists bent. As symptoms get worse, you may notice: Tingling, pain, or weakness with certain activities, such as driving or holding a phone; Difficulty grasping or holding small things; Feeling like your fingers are swollen when they're not. Without treatment, you could lose feeling in some fingers and have permanent weakness in your thumb. But early diagnosis and treatment can help prevent lasting damage. To find out if you have carpal tunnel syndrome, your health care provider will: Ask about your medical history; Ask about your family health history; Do a physical exam; Order tests if needed, such as:...MedlinePlusU.S. National Library of Medicine, 2025
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Carpal tunnel syndrome is compression of the median nerve as it passes through the carpal tunnel in the wrist. Symptoms include pain and paresthesias in the median nerve distribution. Diagnosis is suggested by symptoms and signs and is confirmed by nerve conduction velocity testing. Treatments include ergonomic improvements, analgesia,...Merck & Co., Inc., 2025
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Carpal tunnel syndrome (CTS) is a collection of characteristic symptoms and signs that occurs following compression of the median nerve within the carpal tunnel. Usual symptoms include numbness, paresthesias, and pain in the median nerve distribution.WebMD, 2025
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Carpal tunnel syndrome is caused by pressure on the median nerve. The carpal tunnel is a narrow passageway surrounded by bones and ligaments on the palm side of your hand. When the median nerve is compressed, the symptoms can include numbness, tingling and weakness in the hand and arm.Mayo Foundation for Medical Education and Research, 2025
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Carpal tunnel syndrome (CTS) is a collection of symptoms and signs caused by compression of the median nerve in the carpal tunnel. Typical symptoms include numbness and tingling mainly in the thumb and radial fingers, aching and pain in the anterior wrist and forearm, and clumsiness in the hand.Athenahealth, Inc., 2019
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Carpal tunnel syndrome (CTS), condition of numbness, tingling, or pain in the wrist caused by repetitive flexing or stressing of the fingers or wrist over a long period of time. Possibly the most common repetitive stress injury in the workplace, CTS is frequently associated with the modern office...Encyclopedia Britannica, Inc., 2025
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