Immunologic Factor
edodekin alfa
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to edodekin alfa:
  • A recombinant form of the endogenous heterodimeric cytokine interleukin-12 with potential antineoplastic activity. Edodekin alfa binds to and activates its cell-surface receptor, stimulating the production of interferon-gamma (IFN) which, in turn, induces IFN-gamma-inducible protein-10 (IP-10) and so inhibits tumor angiogenesis. (NCI04)
    NCI
    U.S. National Cancer Institute, 2021
  • One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. Interleukin-12 is made mainly by B lymphocytes and macrophages. It causes other immune cells to make cytokines and increases the growth of T lymphocytes. It may also block the growth of new blood vessels. Interleukin-12 made in the laboratory is used as a biological response modifier to boost the immune system in cancer therapy. Interleukin-12 is a type of cytokine.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
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