Biologically Active Substance
endorphin Audio
en·dor·phin [ en-dawr-fin ]
Subclass of:
Opioid Peptide
Definitions related to endorphins:
  • One of several substances made in the body that can relieve pain and give a feeling of well-being. Endorphins are peptides (small proteins) that bind to opioid receptors in the central nervous system. An endorphin is a type of neurotransmitter.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • One of the three major groups of endogenous opioid peptides. They are large peptides derived from the PRO-OPIOMELANOCORTIN precursor. The known members of this group are alpha-, beta-, and gamma-endorphin. The term endorphin is also sometimes used to refer to all opioid peptides, but the narrower sense is used here; OPIOID PEPTIDES is used for the broader group.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • Substances in the body that reduce pain and create a feeling of well-being.
    Harvard Dictionary of Health Terms
    Harvard Medical Publishing, 2011
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.