Antibiotic
floxacillin
Effect:
Decreased Cell Wall Integrity; Decreased Cell Wall Synthesis & Repair
May Prevent:
Bacterial Infections
May Treat:
Bacterial Infections
Definitions related to floxacillin:
  • Antibiotic analog of CLOXACILLIN.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • (flucloxacillin) A narrow-spectrum, semisynthetic isoxazolyl penicillin with antibacterial activity. Floxacillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.
    NCI
    U.S. National Cancer Institute, 2021
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