Biologically Active Substance
follistatin
Subclass of:
Carrier Proteins
Definitions related to follistatin:
  • A broadly distributed protein that binds directly to ACTIVINS. It functions as an activin antagonist, inhibits FOLLICLE STIMULATING HORMONE secretion, regulates CELL DIFFERENTIATION, and plays an important role in embryogenesis. Follistatin is a single glycosylated polypeptide chain of approximately 37-kDa and is not a member of the inhibin family (INHIBINS). Follistatin also binds and neutralizes many members of the TRANSFORMING GROWTH FACTOR BETA family.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • Activin-binding protein which inhibits the action of activin, and thereby inhibits the release of follicle stimulating hormone.
    CRISP Thesaurus
    National Institutes of Health, 2006
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