A disease in which the thyroid gland does not make enough thyroid hormone.

A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.

Abnormally low levels of thyroid hormone.

Deficiency of thyroid gland activity; characterized by decreased basal metabolic rate, fatigue and lethargy, sensitivity to cold, and menstrual disturbances; untreated it progresses to myxedema; in infants severe hypothyroidism leads to cretinism.

Deficiency of thyroid hormone.

Reduced secretion of thyroid hormone(s) by the thyroid gland.

Too little thyroid hormone. Symptoms include weight gain, constipation, dry skin, and sensitivity to the cold.

Hypothyroidism, or underactive thyroid, happens when your thyroid gland doesn't make enough thyroid hormones to meet your body's needs. Your thyroid is a small, butterfly-shaped gland in the front of your neck. It makes hormones that control the way the body uses energy. These hormones affect nearly every organ in your body and control many of your body's most important functions. For example, they affect your breathing, heart rate, weight, digestion, and moods. Without enough thyroid hormones, many of your body's functions slow down. But there are treatments that can help. Hypothyroidism has several causes. They include: Hashimoto's disease, an autoimmune disorder where your immune system attacks your thyroid. This is the most common cause.; Thyroiditis, inflammation of the thyroid; Congenital hypothyroidism, hypothyroidism that is present at birth; Surgical removal of part or all of the thyroid; Radiation treatment of the thyroid; Certain medicines; In rare cases, a pituitary disease or too much or too little iodine in your diet. You are at higher risk for hypothyroidism if you: Are a woman; Are older than age 60; Have had a thyroid problem before, such as a goiter; Have had surgery to correct a thyroid problem; Have received radiation treatment to the thyroid, neck, or chest; Have a family history of thyroid disease; Were pregnant or had a baby in the past 6 months; Have Turner syndrome, a genetic disorder that affects females; Have pernicious anemia, in which the body cannot make enough healthy red blood cells because it does not have enough vitamin B12; Have Sjogren's syndrome, a disease that causes dry eyes and mouth; Have type 1 diabetes; Have rheumatoid arthritis, an autoimmune disease that affects the joints; Have lupus, a chronic autoimmune disease. The symptoms of hypothyroidism can vary from person to person and may include: Fatigue; Weight gain; A puffy face; Trouble tolerating cold; Joint and muscle pain; Constipation; Dry skin; Dry, thinning hair; Decreased sweating; Heavy or irregular menstrual periods; Fertility problems in women; Depression; Slowed heart rate; Goiter, an enlarged thyroid that may cause your neck to look swollen. Sometimes it can cause trouble with breathing or swallowing. Because hypothyroidism develops slowly, many people don't notice symptoms of the disease for months or even years. Hypothyroidism can contribute to high cholesterol. In rare cases, untreated hypothyroidism can cause myxedema coma. This is a condition in which your body's functions slow down to the point that it becomes life-threatening. During pregnancy, hypothyroidism can cause complications, such as premature birth, high blood pressure in pregnancy, and miscarriage. It can also slow the baby's growth and development. Your health care provider may use many tools to make a diagnosis: A medical history, including asking about your symptoms; A physical exam; Thyroid tests, such as TSH,...

A disorder characterized by a decrease in production of thyroid hormone by the thyroid gland.

Hypothyroidism is thyroid hormone deficiency. It is diagnosed by clinical features such as a typical facial appearance, hoarse slow speech, and dry skin and by low levels of thyroid hormones. Management includes administration of thyroxine.

Hypothyroidism is a common endocrine disorder resulting from deficiency of thyroid hormone. It usually is a primary process in which the thyroid gland is unable to produce sufficient amounts of thyroid hormone.

Hypothyroidism (underactive thyroid) is a condition in which your thyroid gland doesn't produce enough of certain crucial hormones.

Hypothyroidism, a deficiency in hormone production by the thyroid gland. Hypothyroidism usually results from a disorder of the thyroid gland, in which case it is described as primary hypothyroidism. Congenital primary hypothyroidism is caused by lack of or abnormal development of the thyroid in...