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Related terms:
Behcet syndrome
ecchymosis
erythromelalgia
flushing
jaundice
pallor
periarteritis nodosa
phlebitis
pruritus
Disease or Syndrome
livedo reticularis
Subclass of:
Peripheral Vascular Diseases; Skin Diseases, Vascular; Skin Manifestations
Definitions related to livedo reticularis:
  • A condition characterized by a reticular or fishnet pattern on the skin of lower extremities and other parts of the body. This red and blue pattern is due to deoxygenated blood in unstable dermal blood vessels. The condition is intensified by cold exposure and relieved by rewarming.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • A recurrent purple discoloration of the skin that does not blanche and is found in a lacy, network pattern, most often in the lower extremities. It may be aggravated by exposure to cold and is classified as idiopathic or secondary. Secondary livedo reticularis may be a cutaneous manifestation of immune system disorders (e.g., lupus erythematosus, rheumatoid arthritis, cryoglobulinemia, lymphoma, etc), and hematologic disorders (polycythemia vera).
    NCI
    U.S. National Cancer Institute, 2021
  • Livedo reticularis is characterized by the presence of a bluish purple, mottled or netlike pattern in unbroken circles on the skin. Exposure to cold environments usually intensifies the vascular pattern. Presumably, the condition results from slow or stagnant blood flow, vessel-wall pathology, and decreased oxygen tension.
    Human Phenotype Ontology (HPO)
    The Human Phenotype Ontology Project, 2025
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.

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