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What is the Whipple Procedure
Mayo Clinic
Related terms:
appendectomy
colectomy
enterostomy procedure
gastrectomy
gastrostomy
hepatectomy
liver transplantation
pancreas transplantation
pancreatectomy
Therapeutic or Preventive Procedure
pancreaticoduodenectomy
Subclass of:
Digestive System Surgical Procedures
Definitions related to pancreaticoduodenectomy:
  • (whipple procedure) A type of surgery used to treat pancreatic cancer. The head of the pancreas, the duodenum, a portion of the stomach, and other nearby tissues are removed.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • (whipple procedure) Surgical removal of part of the pancreas, duodenum, and distal part of the bile duct. Sometimes, the lower portion of the stomach and the gallbladder are also removed. This procedure is performed for pancreatic, ampullary, duodenal and distal bile duct cancers.
    NCI
    U.S. National Cancer Institute, 2021
  • The excision of the head of the pancreas and the encircling loop of the duodenum to which it is connected.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • A Whipple procedure - also known as a pancreaticoduodenectomy - is a complex operation to remove the head of the pancreas, the first part of the small intestine (duodenum), the gallbladder and the bile duct.
    Mayo Clinic
    Mayo Foundation for Medical Education and Research, 2025
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.

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