Pathologic Function
peripheral edema
pe·riph·er·al e·de·ma [ puh-rif-er-uhl ih-dee-muh ]
Definitions related to peripheral edema:
  • (edema limbs) Swelling due to an excessive accumulation of fluid in the upper or lower extremities.
    NCI
    U.S. National Cancer Institute, 2021
  • Accumulation of an excessive amount of fluid in cells or intercellular tissues of the limbs.
    NICHD Pediatric Terminology
    U.S. National Cancer Institute, 2021
  • Accumulation of fluid in tissues perfused by the peripheral vascular system.
    U.S. FDA Glossary
    U.S. Food & Drug Administration, 2021
  • An abnormal accumulation of interstitial fluid in the soft tissues of the limbs.
    Human Phenotype Ontology (HPO)
    The Human Phenotype Ontology Project, 2025
  • Increased tissue fluid indicated by perceptible pitting indentation on lower leg, foot or sacrum after palpation.
    CDISC Terminology
    Clinical Data Interchange Standards Consortium (CDISC), 2021
  • (edema limbs) A disorder characterized by swelling due to excessive fluid accumulation in the upper or lower extremities.
    Common Terminology Criteria for Adverse Events
    U.S. National Institutes of Health, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.