Organic Chemical
phorbol ester
Subclass of:
Phorbols
Definitions related to phorbol esters:
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Polycyclic compound isolated from croton oil in which two hydroxyl groups on neighboring carbon atoms are esterified to fatty acids. The commonest of these derivatives is phorbol myristoyl acetate (PMA). Potent co carcinogens or tumor promotors, they are diacyl glycerol analogs and activate protein kinase C irreversibly.NCI ThesaurusU.S. National Cancer Institute, 2021
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Tumor-promoting compounds obtained from CROTON OIL (Croton tiglium). Some of these are used in cell biological experiments as activators of protein kinase C.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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