Pharmacologic Substance
prednisolone
[ pred-nis-uh-lohn ]
Brand Names:
Blephamide; Flo-Pred; MILLIPRED; Omnipred; Orapred; Pediapred; Pred Forte; Pred Mild; Pred-G; Prednisol; Prednistab; Surolan; Temaril-P; Veripred
Effect:
Carbohydrate Metabolism Alteration; Decreased Capillary Permeability; Decreased Fibroblast Migration; Decreased Glucocorticoid Secretion; Decreased Leukotriene Activity; Decreased Lysosomal Function; Decreased Polymorphonuclear Leukocyte Migration; Decreased Prostaglandin Activity; Decreased Protein Synthesis; Decreased Thromboxane Activity; Lipid Metabolism Alteration
May Prevent:
Arthritis, Gouty; Arthritis, Rheumatoid
May Treat:
Adrenal Insufficiency;
Anemia, Hemolytic;
Asthma;
Berylliosis;
Brain Neoplasms;
Colitis, Ulcerative;
Collagen Diseases;
Conjunctivitis;
Dermatitis Herpetiformis;
Dermatitis, Atopic;
Edema;
Erythema Multiforme;
Hypercalcemia;
Inflammation;
Leukemia;
Lupus Erythematosus, Systemic;
Multiple Sclerosis;
Mycosis Fungoides;
Nephrotic Syndrome;
Pemphigus;
Rheumatic Diseases;
Sarcoidosis;
Serum Sickness;
Spondylitis, Ankylosing;
Synovitis;
Thrombocytopenia;
Thyroiditis;
Tuberculosis, Pulmonary;
Uveitis
More Information:
Definitions related to prednisolone:
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A drug that lessens inflammation and suppresses the body's immune response. It may also kill cancer cells. Prednisolone is used to treat disorders in many organ systems and to treat the symptoms of several types of leukemia and lymphoma. It is also being studied in the treatment of other types of cancer. Prednisolone is a type of therapeutic glucocorticoid.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2025
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A synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisolone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cells populations. (NCI04)NCIU.S. National Cancer Institute, 2021
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Synthetic glucocorticoid with the general properties of the corticosteroids.CRISP ThesaurusNational Institutes of Health, 2006
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.