Pharmacologic Substance
prinomastat Audio
[ prih-noh-muh-stat ]
Definitions related to prinomastat:
  • A synthetic hydroxamic acid derivative with potential antineoplastic activity. Prinomastat inhibits matrix metalloproteinases (MMPs) (specifically, MMP-2, 9, 13, and 14), thereby inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis. As a lipophilic agent, prinomastat crosses the blood-brain barrier. (NCI04)
    NCI
    U.S. National Cancer Institute, 2021
  • An anticancer drug that belongs to the family of drugs called angiogenesis inhibitors. Prinomastat is a matrix metalloproteinase inhibitor.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
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