Enzyme
rasburicase Audio
[ ras-bur-ih-kays ]
Brand Names:
Elitek
Effect:
Decreased Uric Acid Synthesis
May Treat:
Hyperuricemia; Tumor Lysis Syndrome
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to rasburicase:
  • A drug used to treat high blood levels of uric acid in patients with leukemia, lymphoma, and other types of cancer who are receiving certain types of cancer treatment. It is also being studied in the treatment of other medical conditions. Elitek is a type of recombinant enzyme and a type of urate-lowering drug.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • A recombinant urate oxidase enzyme isolated from a genetically-modified strain of Saccharomyces cerevisiae. Urate oxidase catalyzes the oxidation of uric acid to the excretable metabolite allantoin, a molecule that is 5-10 times more water-soluble than uric acid. An enzyme that occurs endogenously in most mammals, urate oxidase is not found in humans. (NCI04)
    NCI
    U.S. National Cancer Institute, 2021
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