Functional Concept
refractory Audio
re·frac·to·ry [ ri-frak-tuh-ree ]
Etymology:
Latin re = again + frangere = to break
Definitions related to unresponsive to treatment:
  • (refractory) Applies to a sign or symptom that is difficult to treat or cure.
    Human Phenotype Ontology (HPO)
    The Human Phenotype Ontology Project, 2025
  • (refractory) In medicine, describes a disease or condition that does not respond to treatment.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • (refractory) Not responding to treatment.
    NCI
    U.S. National Cancer Institute, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.