Pharmacologic Substance
satraplatin Audio
[ sa-truh-pla-tin ]
Definitions related to satraplatin:
  • A substance being studied in the treatment of prostate and other types of cancer. It contains the metal platinum and may kill cancer cells by damaging their DNA and stopping them from dividing. It is a type of alkylating agent.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • An orally administered third generation platinum compound with potential antineoplastic activity. Satraplatin forms highly reactive, charged, platinum complexes which bind to nucleophilic groups in DNA, inducing intrastrand and interstrand DNA cross-links, as well as DNA-protein cross-links. These cross-links result in cell growth inhibition and apoptosis.
    NCI
    U.S. National Cancer Institute, 2021
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