Laboratory Procedure
spectral karyotyping
spec·tral kar·y·o·typ·ing
Subclass of:
Karyotype determination procedure; Chromosome Painting
Definitions related to spectral karyotyping:
  • A novel karyotyping procedure which is based on the simultaneous hybridization of 24 chromosome-specific painting probes labeled with different fluorochromes or fluorochrome combinations. The measurement of defined emission spectra by means of interferometer-based spectral imaging allows for the definitive discernment of all human chromosomes in different colors. (from Schrock et al., Hum Genet 1997:101:255-62)
    NCI
    U.S. National Cancer Institute, 2021
  • The simultaneous identification of all chromosomes from a cell by fluorescence in situ hybridization (IN SITU HYBRIDIZATION, FLUORESCENCE) with chromosome-specific florescent probes that are discerned by their different emission spectra.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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