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Tetralogy of fallot
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Tetralogy of Fallot (TOF)
Lecturio
Related terms:
aortic coarctation
cor triatriatum
crisscross heart
dextrocardia
patent ductus arteriosus
ebstein anomaly
ectopia cordis
eisenmenger complex
levocardia
Congenital Abnormality
tetralogy of fallot Audio
te·tral·o·gy of Fal·lot [ fa-loh ]
Subclass of:
Congenital Heart Defects
Definitions related to tetralogy of fallot:
  • A combination of congenital heart defects consisting of four key features including VENTRICULAR SEPTAL DEFECTS; PULMONARY STENOSIS; RIGHT VENTRICULAR HYPERTROPHY; and a dextro-positioned AORTA. In this condition, blood from both ventricles (oxygen-rich and oxygen-poor) is pumped into the body often causing CYANOSIS.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • A congenital cardiac malformation comprising pulmonary stenosis, overriding aorta, ventricular septum defect, and right ventricular hypertrophy. The diagnosis of TOF is made if at least three of the four above mentioned features are present.
    Human Phenotype Ontology (HPO)
    The Human Phenotype Ontology Project, 2025
  • A congenital heart disorder characterized by the presence of the following four abnormalities: ventricular septal defect, pulmonary stenosis, overriding aorta, and right ventricular hypertrophy.
    NCI
    U.S. National Cancer Institute, 2021
  • Combination of congenital cardiac defects consisting of pulmonary stenosis, interventricular septal defect, dextroposition of the aorta so that it overrides the interventricular septum and receives venous as well as arterial blood, and right ventricular hypertrophy.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • Defect of the heart which includes all of the following: pulmonary stenosis, interventricular septal defect, dextraposed aorta overriding the ventricular septum, and enlarged right ventricular wall. (Makris S, Solomon HM, Clark R, Shiota K, Barbellion S, Buschmann J, Ema M, Fujiwara M, Grote K, Hazelden KP, Hew KW, Horimoto M, Ooshima Y, Parkinson M, Wise LD. Terminology of developmental abnormalities in common laboratory mammals (Version 2). Part B. Birth Defects Res B Dev Reprod Toxicol. 2009 Aug;86(4):227-327.)
    CDISC Terminology
    Clinical Data Interchange Standards Consortium (CDISC), 2021
  • Tetralogy of Fallot consists of 4 features: a large ventricular septal defect, right ventricular outflow tract obstruction and pulmonic valve stenosis, right ventricular hypertrophy, and over-riding of the aorta. Symptoms include cyanosis, dyspnea with feeding, poor growth, and hypercyanotic "tet" spells (sudden, potentially lethal...
    Merck Manuals
    Merck & Co., Inc., 2025
  • Tetralogy of Fallot (TOF) is one of the most common congenital heart disorders (CHDs). This condition is classified as a cyanotic heart disorder, because tetralogy of Fallot results in an inadequate flow of blood to the lungs for oxygenation (right-to-left shunt).
    Medscape
    WebMD, 2025
  • Tetralogy of Fallot (teh-TRAL-uh-jee of fuh-LOW) is a rare condition caused by a combination of four heart defects that are present at birth (congenital).
    Mayo Clinic
    Mayo Foundation for Medical Education and Research, 2025
  • Tetralogy of Fallot is a complex congenital heart defect characterized by a large ventricular septal defect (hole between the right and left ventricles), pulmonary stenosis (narrowing of the valve and artery that connect the heart with the lungs), an overriding aorta (the aorta - the artery that carries oxygen-rich blood to the body - is...
    NIH Genetic and Rare Diseases
    National Center for Advancing Translational Sciences
  • Tetralogy of Fallot (TOF) is a congenital cardiac malformation. The key morphologic abnormality is anterior and cephalad deviation of the muscular outlet of the ventricular septum, which causes the 4 classic findings: (1) a malalignment ventricular septal defect (VSD), (2) aorta overriding the VSD, (3) right ventricular outflow tract...
    Epocrates
    Athenahealth, Inc., 2019
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