Pharmacologic Substance
ticlopidine
Brand Names:
Ticlid
Effect:
Decreased Platelet Aggregation
May Prevent:
Ischemia; Stroke; Thromboembolism; Venous Thrombosis
May Treat:
Intracranial Embolism and Thrombosis
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to ticlopidine:
  • A thienopyridine derivative with anticoagulant activity. Ticlopidine inhibits adenosine-diphosphate (ADP) binding to its platelet receptor. This prevents ADP activation and inhibits platelet expression of the glycoprotein (GP) IIb/IIIA receptors, binding of fibrinogen to platelet glycoprotein GP IIb-IIIa and platelet-platelet interaction. This results in increased bleeding time.
    NCI
    U.S. National Cancer Institute, 2021
  • An antiplatelet drug that prevents the formation of blood clots.
    Harvard Dictionary of Health Terms
    Harvard Medical Publishing, 2011
  • An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.