• 1. antigens that may be frequently associated with tumors or may be specifically found on tumor cells of the same origin (tumor specific); 2. tumor antigens may also be associated with replication and transformation by certain DNA tumor viruses, including adenoviruses and papovaviruses. Neoantigens. Any immunologically detectable marker whose presence or amount indicates the presence of a tumor.
  NCI
  U.S. National Cancer Institute, 2021
• Proteins, glycoproteins or lipoprotein moieties on surfaces of tumor cells that are usually identified by monoclonal antibodies.
  CRISP Thesaurus
  National Institutes of Health, 2006
• (tumor-specific antigen) A protein or other molecule that is unique to cancer cells or is much more abundant in them. These molecules are usually found in the plasma (outer) membrane, and they are thought to be potential targets for immunotherapy or other types of anticancer treatment.
  NCI Dictionary of Cancer Terms
  U.S. National Cancer Institute, 2021
• Many tumor cells produce antigens, which may be released in the bloodstream or remain on the cell surface. Any molecule capable of being recognized by the immune system is considered an antigen. Antigens have been identified in most of the human cancers, including Burkitt lymphoma, neuroblastoma, melanoma, osteosarcoma, renal cell...
  Merck Manuals
  Merck & Co., Inc., 2025