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Frontiers in Public Health 2021Disinfection is a key element in controlling infections. Fogging, also known as fumigation, is one of the most effective chemical disinfection methods. Peracetic acid...
Disinfection is a key element in controlling infections. Fogging, also known as fumigation, is one of the most effective chemical disinfection methods. Peracetic acid (PAA) is a powerful oxidant with bactericidal and fungicidal properties. The aim of this study is to determine the type of bacteria and fungi present in educational institutions and whether disinfection by PAA fumigation in these institutions is also effective and useful, as demonstrated previously in healthcare centers. This study was carried out in five kindergartens and five primary schools in Bialystok, Poland. Three rooms have been selected in each of these educational institutions, and the disinfection was carried out in 30 rooms in total. Fogging with PAA was performed in selected rooms. Before and after disinfection, samples were collected from four surfaces: walls, tables, doors, and chair backs. Most frequently detected microorganisms in schools and kindergartens were ssp. . In addition, ssp. were the most prevalent in kindergartens, whereas was the most prevalent in schools. Comparison of the bacterial flora of schools and kindergartens showed statistically significant differences in the prevalence of bacteria on different surfaces. A significant decrease in the number of colonies after disinfection was observed on all surfaces ( < 0.05). In addition, the calculated effectiveness of disinfection was 99.7% in kindergartens and 99.3% in schools. The results indicate that fogging of PAA is a highly effective method of surface disinfection in kindergartens and schools.
Topics: Acinetobacter; Actinobacteria; Micrococcaceae; Paracoccus; Peracetic Acid; Schools; Staphylococcus
PubMed: 34604154
DOI: 10.3389/fpubh.2021.697917 -
Applied and Environmental Microbiology Jul 2023SARS-CoV-2 is primarily a respiratory virus that can potentially be transmitted through fomites. Sodium hypochlorite (NaOCl) and peracetic acid (PAA) are widely used...
SARS-CoV-2 is primarily a respiratory virus that can potentially be transmitted through fomites. Sodium hypochlorite (NaOCl) and peracetic acid (PAA) are widely used disinfectants on surfaces in diverse settings such as hospitals and food production facilities. The objectives of this study were to investigate the virucidal efficacy of NaOCl and PAA against SARS-CoV-2 using the ASTM standard methods. In the suspension assay, NaOCl and PAA (5, 50, and 200 ppm) were tested against SARS-CoV-2 in the presence/absence of soil load after 1 min of contact time. In the carrier assay, NaOCl and PAA were tested at 200, 400, 600, and 1,000 ppm for 1 min and 200 and 1,000 ppm for 5 and 10 min. Stainless steel (SS) and high-density polyethylene (HDPE) disks were used as carriers. The virus was suspended in soil load and the disinfectants were prepared in 300 ppm of hard water. Virus quantification was done by TCID50 assay using Vero-E6 cell line. NaOCl and PAA were effective (> 3 log reduction in infectious virus) at 50 ppm in the absence of soil load. However, in the presence of soil load, 200 ppm was required for > 3 log reduction in virus infectivity. In contrast, NaOCl and PAA at 200 ppm and with a 1-min contact time were not effective against SARS-CoV-2 on either SS or HDPE surfaces. PAA at 200 ppm for 10 min was effective against SARS-CoV-2 on SS and HDPE surfaces, whereas NaOCl required 1,000 ppm for 10 min to be effective against SARS-CoV-2 on both surfaces. In the context of the COVID-19 pandemic, the World Health Organization (WHO) recommended the use of chlorine-based products such as sodium hypochlorite (NaOCl) at 1,000 ppm for a minimum of 1 min to disinfect environmental surfaces. However, this recommendation was not based on validated studies on the actual SARS-CoV-2 itself. In fact, over half of the chemical disinfectants, including many peracetic acid products, listed in EPA List N were approved based on "kills a harder-to-kill pathogen" without further validation on SARS-CoV-2. Research on SARS-CoV-2 is restricted to BSL3 laboratories and the urgency of tackling the pandemic might explain the lack of studies on the actual virus. Our results show that the WHO recommendation of 1 min contact time with 1,000 ppm NaOCl is not effective against SARS-CoV-2 on surfaces. Also, our results indicate that PAA is effective against SARS-CoV-2 on surfaces and can be used as safer and more environmentally friendly alternative to NaOCl at a lower concentration.
Topics: Humans; Sodium Hypochlorite; Peracetic Acid; SARS-CoV-2; Pandemics; Polyethylene; COVID-19; Disinfectants
PubMed: 37347194
DOI: 10.1128/aem.00622-23 -
Water Research Jan 2021Peracetic acid (PAA) has attracted growing attention as an alternative oxidant and disinfectant in wastewater treatment due to the increased demand to reduce chlorine... (Review)
Review
Peracetic acid (PAA) has attracted growing attention as an alternative oxidant and disinfectant in wastewater treatment due to the increased demand to reduce chlorine usage and control disinfection byproducts (DBPs). These applications have stimulated new investigations on PAA-based advanced oxidation processes (AOPs), which can enhance water disinfection and remove micropollutants. The purpose of this review is to conduct a comprehensive analysis of scientific information and experimental data reported in recent years on the applications of PAA-based AOPs for the removal of chemical and microbiological micropollutants from water and wastewater. Various methods of PAA activation, including the supply of external energy and metal/metal-free catalysts, as well as their activation mechanisms are discussed. Then, a review on the usage of PAA-based AOPs for contaminant degradation is given. The degradation mechanisms of organic compounds and the influence of the controlling parameters of PAA-based treatment systems are summarized and discussed. Concurrently, the application of PAA-based AOPs for water disinfection and the related mechanisms of microorganism inactivation are also reviewed. Since combining UV light with PAA is the most commonly investigated PAA-based AOP for simultaneous pathogen inactivation and micropollutant oxidation, we have also focused on PAA microbial inactivation kinetics, together with the effects of key experimental parameters on the process. Moreover, we have discussed the advantages and disadvantages of UV/PAA as an AOP against the well-known and established UV/HO. Finally, the knowledge gaps, challenges, and new opportunities for research in this field are discussed. This critical review will facilitate an in-depth understanding of the PAA-based AOPs for water and wastewater treatment and provide useful perspectives for future research and development for PAA-based technologies.
Topics: Decontamination; Disinfection; Hydrogen Peroxide; Peracetic Acid; Ultraviolet Rays; Wastewater; Water; Water Pollutants, Chemical; Water Purification
PubMed: 33069949
DOI: 10.1016/j.watres.2020.116479 -
Frontiers in Public Health 2022Cars with air conditioning systems have become the norm, but these systems can be dangerous for human health as a result of the accumulation of different microorganisms,...
Cars with air conditioning systems have become the norm, but these systems can be dangerous for human health as a result of the accumulation of different microorganisms, including pathogenic ones, causing severe allergy or inflammation problems. The novel purpose of this study is 2-fold: on the one hand, to test different disinfection agents on a new area, that is, automobile cabins, and on the other, to compare activity in the gas phase of these agents for disinfection of car air conditioning and cabin surfaces. This study shown that tested disinfectant agents dedicated for decontamination medical areas (agent based on peracetic acid and an agent containing didecyldimethylammonium chloride, 2-phenoxyethanol with cinnamaldehyde) can be successfully used for disinfection car air conditioning and cabin surfaces. Both disinfectants were examined in comparison to a commercial "ready-to-use" spray from a local supermarket dedicated to car air conditioning disinfection. Our research found that very effective agents in this regard were acid stabilized by hydrogen peroxide applied by fumigator, and a combination of didecyldimethylammonium chloride, 2-phenoxyethanol, and cinnamaldehyde applied by atomizer. Tested disinfection procedures of car air conditioning significantly influence the quality of cabin air and surfaces by reducing the amount of microorganisms. The comparison of disinfection properties studied agents in the gas phase reveal statistically significant differences between it effect for disinfection car air conditioning and cabin surfaces. Our research found that very effective agents in this regard were acid stabilized by hydrogen peroxide applied by fumigator, and a combination of didecyldimethylammonium chloride, 2-phenoxyethanol, and cinnamaldehyde applied by atomizer. Tested disinfection procedures of car air conditioning significantly influence the quality of cabin air and surfaces by reducing the amount of microorganisms.
Topics: Disinfectants; Disinfection; Humans; Hydrogen Peroxide; Peracetic Acid
PubMed: 35284381
DOI: 10.3389/fpubh.2022.820816 -
The Science of the Total Environment Nov 2021The growing demand to reduce chlorine usage and control disinfection byproducts increased the development of new strategies in wastewater treatments. Organic peracids...
The growing demand to reduce chlorine usage and control disinfection byproducts increased the development of new strategies in wastewater treatments. Organic peracids are increasingly attracting interest in disinfection activities as a promising alternative to chlorine and chlorine-based agents. In this study, we assessed the antimicrobial properties against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) of a new organic peracid, permaleic acid (PMA) compared with the reference peracetic acid (PAA). Disinfectant properties were evaluated by i) disk diffusion agar, ii) broth microdilution, iii) antibiofilm properties. PMA demonstrated a 10- and 5-fold decrease in the microbial inhibitory concentration (MIC) value against E. coli and S. aureus respectively, compared to PAA. Results showed greater efficacy of PMA regarding wastewater (WW) and treated wastewater (TWW) disinfection at low concentrations. Furthermore, the biofilm degradation ability was only observed following PMA treatment, for both strains. Bacterial regrowth from biofilm matrix after PAA and PMA disinfection, in the absence and presence of organic matter, was evaluated. PMA was more efficient than PAA to prevent the regrowth of planktonic cells of S. aureus and E. coli. After PAA and PMA treatment, in the presence of organic matter, the bacterial regrowth inhibition was maintained up to 10 and 5 g/L, respectively. Based on these results, PMA could be used as a valid alternative to the currently used disinfection methods.
Topics: Disinfectants; Disinfection; Escherichia coli; Peracetic Acid; Staphylococcus aureus
PubMed: 34311370
DOI: 10.1016/j.scitotenv.2021.149206 -
Occupational Medicine (Oxford, England) Dec 2019
Topics: Asthma, Occupational; Humans; Hydrogen Peroxide; Peracetic Acid
PubMed: 32058572
DOI: 10.1093/occmed/kqz139 -
Molecules (Basel, Switzerland) Oct 2022Chlorinated compounds are usually applied in vegetable sanitization, but there are concerns about their application. Thus, this study aimed to evaluate ultrasound (50...
Chlorinated compounds are usually applied in vegetable sanitization, but there are concerns about their application. Thus, this study aimed to evaluate ultrasound (50 kHz), acetic acid (1000; 2000 mg/L), and peracetic acid (20 mg/L) and their combination as alternative treatments to 200 mg/L sodium dichloroisocyanurate. The overall microbial, physicochemical, and nutritional quality of kale stored at 7 °C were assessed. The impact on Typhimurium was verified by plate-counting and scanning electron microscopy. Ultrasound combined with peracetic acid exhibited higher reductions in aerobic mesophiles, molds and yeasts, and coliforms at 35 °C (2.6; 2.4; 2.6 log CFU/g, respectively). Microbial counts remained stable during storage. The highest reduction in occurred with the combination of ultrasound and acetic acid at 1000 mg/L and acetic acid at 2000 mg/L (2.8; 3.8 log CFU/g, respectively). No synergistic effect was observed with the combination of treatments. The cellular morphology of the pathogen altered after combinations of ultrasound and acetic acid at 2000 mg/L and peracetic acid. No changes in titratable total acidity, mass loss, vitamin C, or total phenolic compounds occurred. Alternative treatments presented equal to or greater efficacies than chlorinated compounds, so they could potentially be used for the decontamination of kale.
Topics: Peracetic Acid; Brassica; Acetic Acid; Disinfectants; Decontamination; Disinfection; Food Microbiology; Colony Count, Microbial; Chlorine Compounds; Salmonella typhimurium; Ascorbic Acid; Chlorine; Food Handling
PubMed: 36296611
DOI: 10.3390/molecules27207019 -
Journal of Hazardous Materials Feb 2022The reactivity of peracetic acid (PAA) alone, and PAA exposed to ultraviolet radiation (UV), was investigated on Microcystis aeruginosa cells, and on microcystin-LR and...
The reactivity of peracetic acid (PAA) alone, and PAA exposed to ultraviolet radiation (UV), was investigated on Microcystis aeruginosa cells, and on microcystin-LR and -RR. Reaction rates between PAA and MC-LR (k = 3.46 M s) and MC-RR (k = 2.67 M s) were determined in an unbuffered acidic solution, and they are approximately 35-45 times lower than a previously reported reaction rate between MC-LR and chlorine at pH 6. Peracetic acid reacted with M. aeruginosa cells as a function of PAA and cell concentrations, with 10 mg/L PAA resulting in 1-log reduction of total MC-LR within 15 min. Advanced oxidation by UV/PAA readily degraded MC-LR and MC-RR, outperforming UV/HO at pH 7.7 by > 50% on an equimolar basis. Indirect photolysis at this pH is due to OH and organic radicals, as determined by trials in the presence of excess tert-butanol to scavenge OH. The process is less effective when the pH departs from neutral conditions (5.9 or 10.6) due to the decreased effects of both radicals. These findings suggest that PAA alone might be a viable option for cyanobacteria and microcystins control in preoxidation applications and that UV/PAA is an effective process for degrading MC-LR and MC-RR at neutral pH.
Topics: Hydrogen Peroxide; Marine Toxins; Microcystins; Microcystis; Peracetic Acid; Pseudomonas aeruginosa; Ultraviolet Rays
PubMed: 34687995
DOI: 10.1016/j.jhazmat.2021.127357 -
Molecules (Basel, Switzerland) May 2020Numerous substances from different chemical sectors, from the pharmaceutical industry to the many consumer products available for everyday usage, can find their way into...
Numerous substances from different chemical sectors, from the pharmaceutical industry to the many consumer products available for everyday usage, can find their way into water intended for human consumption and wastewater, and can have adverse effects on the environment and human health. Thus, the disinfection process is an essential stage in water and wastewater treatment plants to destroy pathogenic microorganisms but it can form degradation byproducts. Sodium hypochlorite is the most common disinfectant, but the most important drawback associated with this kind of compound is the generation of toxic disinfection byproducts. Many studies have been carried out to identify alternative disinfectants, and in the last few years, peracetic acid has been highlighted as a feasible solution, particularly in wastewater treatment. This study compares the transformations of five emerging pollutants (caffeine, tramadol, irbesartan, diclofenac, trazodone) treated with peracetic acid, to evaluate their degradation and the possible formation of byproducts with those obtained with sodium hypochlorite. Although peracetic acid has many advantages, including a wide field of use against microorganisms and a low toxicity towards animal and plant organisms, it is not as effective in the degradation of the considered pollutants. These ones are recovered substantially and are unchanged quantitatively, producing a very low number of byproducts.
Topics: Peracetic Acid; Pharmaceutical Preparations; Sodium Hypochlorite; Wastewater; Water Purification
PubMed: 32414067
DOI: 10.3390/molecules25102294 -
Bioresource Technology Jan 2021Lignocellulose fractionation is a primary treatment to enhance cellulose accessibility and multi-component use. Herein, the development of a one-step fractionation is...
Lignocellulose fractionation is a primary treatment to enhance cellulose accessibility and multi-component use. Herein, the development of a one-step fractionation is reported for cellulose enrichment from corn stover using a low concentration of peracetic acid combined with maleic acid (PAM). The effects of pretreatment parameters on the contents of cellulose, hemicellulose, and lignin were investigated. After cooking for 1 h at 130 °C with 1.5 wt% peracetic acid and 3 wt% maleic acid, 86.83% of corn stover cellulose remained in the solid residue while 88.21% of hemicellulose and 87.77% of lignin dissolved into the aqueous liquid. Hemicellulose was primarily hydrolyzed into xylose with 84.58% recovered during the PAM process. The cellulose-rich residue was enzymatically hydrolyzed with a glucose yield of 89.65%, which was two to three times that of untreated substrate. Generally, the proposed process offers a promising approach for efficient fractionation of lignocellulose under mild and environmental-friendly conditions.
Topics: Cellulose; Hydrolysis; Lignin; Maleates; Peracetic Acid; Zea mays
PubMed: 33157440
DOI: 10.1016/j.biortech.2020.124306