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Scientific Reports Mar 2024Globally, there has been a dramatic increase in the geriatric population. Sadly, this populace is highly prone to develop various ocular morbidities putting pressure on...
Globally, there has been a dramatic increase in the geriatric population. Sadly, this populace is highly prone to develop various ocular morbidities putting pressure on the strained eye care delivery system especially in low-income countries. Hence, the aim of this study was to determine the distribution of ocular morbidities among elderly. The study was a retrospective cross-sectional study conducted at Mzuzu Central Hospital in Malawi. We retrieved data from the hospital's Ophthalmology out-patient registry from January 2021 to December 2021. We recruited all 970 elderly patients who visited the clinic during the period of study. Data entry and analysis was done employing SPSS (v.26). More males than females had ocular morbidities. Cataract 400 (41.2%) was the most prevalent ocular morbidity followed by glaucoma 189 (19.5%), pinguecula 48 (4.9%) and allergic conjunctivitis 43 (4.4%). Anterior segment eye diseases were common 714 (73.6%). The prevalence of cataract, glaucoma, refractive error and allergic conjunctivitis was significantly associated with sex (p < 0.05). Age association was found with the prevalence of cataract, glaucoma, pinguecula, allergic conjunctivitis and corneal scar (p < 0.05). The pattern of eye diseases is endemic to the country. More resources should be targeting cataract and glaucoma among the age group.
Topics: Male; Female; Humans; Aged; Conjunctivitis, Allergic; Tertiary Care Centers; Cross-Sectional Studies; Retrospective Studies; Malawi; Pinguecula; Eye Diseases; Glaucoma; Cataract; Prevalence; Outpatients
PubMed: 38509142
DOI: 10.1038/s41598-024-55538-z -
Health Science Reports Jun 2023The population of older adults is growing dramatically. Sadly, this populace is highly prone to develop various ocular morbidities, which if left unattended can lead to...
BACKGROUND
The population of older adults is growing dramatically. Sadly, this populace is highly prone to develop various ocular morbidities, which if left unattended can lead to blindness.
AIM
To determine the distribution of ocular morbidities among older adults at a secondary hospital in Malawi.
METHODS
This was a retrospective cross-sectional study conducted at Mzimba North District Hospital in Malawi. We retrieved 314 patient records from the hospital's ophthalmic outpatient registry from August 2020 to July 2022 using a nonprobability census sampling technique. Data entry and analysis were done employing SPSS (v.26).
RESULTS
More females 164 (52.2%) than males 150 (47.8%) had ocular morbidities. Cataract 108 (34.4%) was the most common ocular morbidity followed by allergic conjunctivitis 104 (33.1%), then pingueculae 44 (14%), and glaucoma 8 (2.5%) Cataract showed a statistically significant difference between males and females ( < 0.05). And Glaucoma portrayed a statistically significant variation according to age groups ( < 0.05). According to the time of the year, most cases were attended to in March compared to August.
CONCLUSION
The majority of blinding conditions among the elderly in Malawi are preventable similar to other geographical settings. Therefore, it is feasible to enhance the quality of life for senior Malawians and lessen the impact of blindness on individuals, families, and communities by addressing preventable causes of blindness through focused interventions.
PubMed: 37275671
DOI: 10.1002/hsr2.1304 -
American Journal of Ophthalmology Feb 2015To evaluate whether the handheld in vivo reflectance confocal microscopy that has been recently developed for the study of skin tumors is suitable for the diagnosis of... (Observational Study)
Observational Study
PURPOSE
To evaluate whether the handheld in vivo reflectance confocal microscopy that has been recently developed for the study of skin tumors is suitable for the diagnosis of conjunctival tumors.
DESIGN
Prospective study, observational case series.
METHODS
We prospectively evaluated the reflectance confocal microscopy features of 53 conjunctival lesions clinically suspicious for tumors of 46 patients referred to the University Hospital of Saint-Etienne (France) by using the handheld device. Twenty-three lesions were excised (3 nevi, 10 melanomas, 5 squamous cell carcinoma, 2 lymphomas, and 3 pinguecula/pterygium) while the other 30, presenting no reflectance confocal microscopy malignant features, were under follow-up for at least 1 year. Clinical reflectance confocal microscopy and histologic diagnosis were compared.
RESULTS
In vivo reflectance confocal microscopy diagnosis was in agreement with the histologic diagnosis in all cases and none of the lesions that were not excised show any clinical progression under follow-up.
CONCLUSION
In vivo reflectance confocal microscopy with a handheld dermatology-dedicated microscope can play a role in the noninvasive diagnosis of conjunctival lesions. Further studies should be performed to better define the diagnostic ability of this technique.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Conjunctival Neoplasms; Female; Humans; Lymphoma; Male; Melanoma; Microscopy, Confocal; Middle Aged; Nevus; Prospective Studies; Young Adult
PubMed: 25447117
DOI: 10.1016/j.ajo.2014.10.031 -
International Journal of Surgery Case... Mar 2024Ocular surface squamous neoplasia (OSSN) may have atypical or unusual presentations and may attain large sizes especially in cases of delayed presentation resulting in...
Variable presentations of six conjunctival/limbal ocular surface squamous neoplasia (OSSN) cases: How good is our clinical judgment evidenced by the correlation to the histopathological findings and diagnosis?
INTRODUCTION
Ocular surface squamous neoplasia (OSSN) may have atypical or unusual presentations and may attain large sizes especially in cases of delayed presentation resulting in late diagnosis, treatment, and eventual guarded visual prognosis. We are reporting an interesting cases series of OSSN with variable clinical presentations to highlight the importance of the pre-operative clinical judgment and tissue diagnosis.
PRESENTATION OF CASES
Six patients (4 females and 2 males; mean age 59 years; range 42-79 years) were included with suspicious conjunctival lesions. The maximum dimension of the lesions was 17 mm. The initial suspected pre-operative clinical diagnosis -other than OSSN- included pterygium/pinguecula (n = 2), benign squamous papilloma (n = 1), cyst versus pyogenic granuloma (n = 1), and lymphoma (n = 1). This work has been reported in line with the PROCESS criteria.
DISCUSSION
The final histopathological diagnosis was unexpectedly invasive squamous cell carcinoma (SCC) in 4, one SCC in-situ, and squamous dysplasia in one. The primary treatment included MMC 0.02 % for 2 cycles for chemo-reduction in one of the cases where OSSN was suspected. Excisional biopsy was performed eventually for all lesions with application of one or more of the following modalities: MMC 0.02 %, absolute alcohol 99 %, and cryotherapy to the conjunctival margin. No tumor recurrence was noted in any of the patients after an average period of follow-up of 26 months. Even though the outcome was good, tumor-related morbidity and delay in the referral by general ophthalmologists are to be considered.
CONCLUSION
Conjunctival OSSN has wide presentation clinically and can be challenging in terms of diagnosis. Histopathological evaluation is essential for a definitive diagnosis and treatment. Accurate clinical diagnosis might affect the management plan with consideration for topical therapeutic modalities, however, these cases are best managed by wide excision using the no-touch technique and double-freeze-thaw cryotherapy to the conjunctiva with consideration of topical chemotherapy.
PubMed: 38330700
DOI: 10.1016/j.ijscr.2024.109359 -
Archivos de La Sociedad Espanola de... Oct 2014The pinguecula is a degenerative lesion which is usually asymptomatic, except when it is associated with an inflammatory reaction. We present 2 clinical cases of...
CLINICAL CASES
The pinguecula is a degenerative lesion which is usually asymptomatic, except when it is associated with an inflammatory reaction. We present 2 clinical cases of patients that had symptomatic pinguecula, in which intra-lesional betamethasone in depot form was used as treatment, obtaining a significant clinical improvement.
DISCUSSION
The administration of intra-lesional betamethasone in depot form may be a good alternative for the treatment of the symptomatic pinguecula.
Topics: Adult; Betamethasone; Female; Glucocorticoids; Humans; Injections, Intralesional; Pinguecula
PubMed: 24269437
DOI: 10.1016/j.oftal.2013.04.012 -
Turkish Journal of Ophthalmology Jun 2018A 21-year-old male patient with no history of systemic disease or drug use presented to our clinic with redness and pain in the right eye. Best corrected visual acuity...
A 21-year-old male patient with no history of systemic disease or drug use presented to our clinic with redness and pain in the right eye. Best corrected visual acuity was 20/20 in both eyes. Inflamed pinguecula was observed on slit-lamp examination and the patient was prescribed ophthalmic nepafenac eye drops. After instilling the drops that day and the next day, the patient presented again due to pruritus and rash. Upon consultation with the dermatology department, the patient was diagnosed with drug-induced allergic urticaria and the nepafenac drops were discontinued. Although urticaria has been reported as a side effect after systemic non-steroidal anti-inflammatory drug (NSAID) use, such a reaction has not been reported with an ophthalmic NSAID and ours is the first reported case of urticaria following ophthalmic nepafenac use. This unique case highlights the fact that ophthalmologists must also keep urticaria in mind as a potential side effect when prescribing this drug.
PubMed: 29988879
DOI: 10.4274/tjo.78614 -
Canadian Journal of Ophthalmology.... Aug 2016
Topics: Adult; Aged; Amnion; Female; Humans; Ophthalmologic Surgical Procedures; Pinguecula; Pterygium; Scleral Diseases
PubMed: 27521676
DOI: 10.1016/j.jcjo.2016.03.004